Cushing’s syndrome and adrenal suppression following topical corticosteroid use
Keywords:
Adrenal insufficiency,, Corticosteroid, Iatrogenic cushing’s syndromeAbstract
The extended use of topical corticosteroids, particularly in young children, may cause suppression of the hypothalamo-pituitary-adrenal axis. Here, three cases of iatrogenic adrenal suppression resulting from topical corticosteroids are presented.
References
Tiwari A, Goel M, Gohiya P. Topical-steroidinduced iatrogenic Cushing syndrome in the pediatric age group: A rare case report. Indian J Endocrinol Metab 2013; 17: S257–S258.
Findlay CA, Macdonald JF, Wallace AM, et al. Childhood Cushing's syndrome induced by betamethasone nose drops, and repeat prescriptions, BMJ Volume 317 12 September 1998.
Hopkins R L, Leinung M C. Exogenous Cushing’s Syndrome and Glucocorticoid Withdrawal. Endocrinol Metab Clin N Am 2005; 34: 371–384.
Semiz S, Balci YI, Ergin S, Candemir M, Polat A. Two cases of Cushing's syndrome due to overuse of topical steroid in the diaper area. Ann Pharma cother 2008; 42(12): 1903-7.
Perry RJ, Findlay CA, Donaldson MD. Cushing's syndrome, growth impairment, and occult adrenal suppression associated with intranasal steroids. Arch Dis Child 2002l; 87(1): 45-8.
Dutta D, Shivaprasad KS, Chowdhury S. Iatrogenic Cushing’s Syndrome Following Short-Term Intranasal Steroid Use. J Clin Res Pediatr Endocrinol 2012; 4(3): 157–159.
Price J. The role of inhaled corticosteroids in children with asthma. Arch Dis Child 2000; 82: ii10-ii14.
Coureau B, Bussières JF, Tremblay S. Cushing's syndrome induced by misuse of moderate- to highpotency topical corticosteroids Endocrine. 2010; 38(3): 328-34.
Katar S, Akdeniz S, Özbek M N, Yaramiş A. Infantile Iatrogenic Cushing's Syndrome, Indian J Dermatol 2008; 53(4): 190–191.
Namburu RP, Karthik TS ,Reddy AP. Iatrogenic Cushing’sSyndrome in an Infant, Journal of Clinical and Diagnostic Research 2013; 7(2): 353-354.
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